Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
ALEXANDRA GLOBAL MASTER FUND LTD
  2. Issuer Name and Ticker or Trading Symbol
VIRAGEN INC [VRA]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
CITCO BUILDING, WICKAMS CAY, P.O. BOX 662
3. Date of Earliest Transaction (Month/Day/Year)
03/20/2007
(Street)

ROAD TOWN, TORTOLA, D8 
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 03/20/2007   S   74,300 D $ 0.05 35,463,339 (1) D (1)  
Common Stock 03/20/2007   S   398,650 D $ 0.05 35,064,689 (1) D (1)  
Common Stock 03/21/2007   S   5,064,789 D $ 0.0223 29,999,900 (1) D (1)  
Common Stock 03/21/2007   S   20,500,000 D $ 0.0237 9,499,900 (1) D (1)  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
ALEXANDRA GLOBAL MASTER FUND LTD
CITCO BUILDING, WICKAMS CAY
P.O. BOX 662
ROAD TOWN, TORTOLA, D8 
    X    
ALEXANDRA INVESTMENT MANAGEMENT LLC
767 THIRD AVENUE
39TH FLOOR
NEW YORK, NY 10017
    X    
Filimonov Mikhail
767 THIRD AVENUE, 39TH FLOOR
NEW YORK, NY 10017
    X    

Signatures

 ALEXANDRA GLOBAL MASTER FUND LTD., By: ALEXANDRA INVESTMENT MANAGEMENT, LLC, as Investment Advisor, By: /s/ Mikhail Filimonov, its Chairman and Chief Executive Officer   03/22/2007
**Signature of Reporting Person Date

 ALEXANDRA INVESTMENT MANAGEMENT, LLC, By: /s/ Mikhail Filimonov, its Chairman and Chief Executive Officer   03/22/2007
**Signature of Reporting Person Date

 /s/ Mikhail Filimonov   03/22/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Alexandra Global Master Fund Ltd. ("Alexandra") is the direct beneficial owner of the securities. Alexandra Investment Management, LLC ("AIM") is the investment advisor to Alexandra. Mikhail Filimonov is the Chairman, Chief Executive Officer, Chief Investment Officer and a Managing Member of AIM. By reason of these relationships, AIM and Mikhail Filimonov may be deemed to beneficially own the securities beneficially owned by Alexandra. AIM and Mikhail Filimonov each disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interests therein.
 
Remarks:
Joint Filer Information

Each of the following filers has designated Alexandra Global Master Fund Ltd. as the "Designated Filer" for purposes of this Form 4.

           (i)     Alexandra Investment Management, LLC
                   767 Third Avenue, 39th Floor, New York, NY 10017

           (ii)    Mikhail Filimonov
                   767 Third Avenue, 39th Floor, New York, NY 10017

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