SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

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                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                      SECURITIES EXCHANGE ACT OF 1934

       Date of report (Date of earliest event reported): January 18, 2002
                                                         ----------------

                               CYTOGEN CORPORATION
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               (Exact Name of Registrant as Specified in Charter)

       Delaware                      000-14879                  222322400
---------------------------  --------------------------  -----------------------
(State or Other Jurisdiction  (Commission File Number)        (I.R.S. Employer
    of Incorporation)                                       Identification No.)

       600 College Road East, CN 5308, Princeton, NJ           08540
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          (Address of Principal Executive Offices)            (Zip Code)

       Registrant's telephone number, including area code: (609) 750-8200
                                                           --------------





ITEM 5.   OTHER EVENTS.

     On October 25,  2001,  Cytogen  Corporation,  a Delaware  corporation  (the
"Company")  filed a shelf  registration  statement  (File  No.  333-72226)  (the
"Registration   Statement")  on  Form  S-3  with  the  Securities  and  Exchange
Commission (the "Commission") relating to the public offering,  pursuant to Rule
415 under the Securities Act of 1933, as amended (the  "Securities  Act"), of up
to an  aggregate  of  10,000,000  shares of  common  stock of the  Company.  The
Commission declared the Registration Statement effective on November 6, 2001.

     On January 18, 2002, the Company  entered into a Share  Purchase  Agreement
(the "Agreement") with the State of Wisconsin Investment Board ("SWIB") relating
to the issuance and sale of 2,970,665  shares of the Company's  common stock for
an aggregate purchase price of $8.0 million.

     On January 22,  2002,  the Company  filed with the  Commission a prospectus
supplement (the "Prospectus  Supplement") to the Registration Statement pursuant
to Rule 424(b)(2) of the Securities Act, relating to the sale of such shares and
subsequently issued the shares upon closing of the transaction on such date.

     In connection  with its execution of the  Agreement,  the Company agreed to
amend, within thirty days of closing,  its Bylaws and its stock option plans, as
set forth in the Agreement, to, among other things, prohibit,  without requisite
stockholder  approval,  certain grants or adjustments to stock options and stock
appreciation rights.

     Each of the  Agreement  and the related  press release of the Company dated
January  22,  2002  are  attached  hereto  as  Exhibit  10.1 and  Exhibit  99.1,
respectively,   and  are  incorporated   herein  by  reference.   The  foregoing
descriptions of: (i) the Registration Statement;  (ii) the Agreement;  and (iii)
the Prospectus Supplement,  are qualified in their entirety by reference to such
documents.

ITEM 7.   FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

     (c)  Exhibits.

               Exhibit No.  Description
               -----------  -----------

                  10.1      Share  Purchase  Agreement  by  and  between Cytogen
                            Corporation  and  the State of Wisconsin  Investment
                            Board dated  January 18,  2002

                  99.1      Press  release of Cytogen Corporation dated  January
                            22, 2002





                                   SIGNATURES


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly caused this current  report on Form 8-K to be signed on its
behalf by the undersigned hereunto duly authorized.

                                         CYTOGEN CORPORATION


                                         By: /s/ Catherine M. Verna
                                            ------------------------------------
                                            Catherine M. Verna, Esq.
                                            Vice President and General Counsel

Dated:   January 23, 2002





                                  EXHIBIT INDEX


               Exhibit No.   Description
               -----------   -----------

                  10.1       Share  Purchase  Agreement by and  between  Cytogen
                             Corporation  and the State of  Wisconsin Investment
                             Board dated January 18, 2002

                  99.1       Press release of Cytogen Corporation dated January
                             22, 2002