UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C.  20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
				(Amendment No. __1___)

XCYTE Therapies, Inc.
               _____________________________________________
         (Name of Issuer)
         
Common Stock, .001 Par Value
              _______________________________________________
(Title of Class of Securities)

98389F309
              _________________________________________________
(CUSIP Number)


		with a copy to:
Austin W. Marxe		Allen B. Levithan, Esq.
153 East 53rd Street		Lowenstein Sandler PC
New York, New York 10022		65 Livingston Avenue
			Roseland, N.J. 07068
			(973) 597-2406
(Name, Address and Telephone Number of Person 
Authorized to Receive Notices and Communications)

December 31, 2004
(Date of Event which Requires Filing of this Statement)

                                                                                
Check the appropriate box to designate the rule pursuant to which this 
Schedule is filed:

	____	Rule 13d-1(b)
	_x__	Rule 13d-1(c)
	____	Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting 
person's initial filing on this form with respect to the subject class 
of securities, and for any subsequent amendment containing information 
which would alter disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not 
be deemed to be ?filed? for the purpose of Section 18 of the Securities 
Exchange Act of 1934 (?Act?) or otherwise subject to the liabilities of 
that section of the Act but shall be subject to all other provisions of 
the Act (however, see the Notes).



Cusip No. 98389F309       13G                           Page 2 of 6 
Pages
1.Names of Reporting Persons.  I.R.S. Identification Nos. of above 
persons (entities only):
	
	Austin W. Marxe and David M. Greenhouse

	
	2.	Check the Appropriate Box if a Member of a Group (See 
Instructions):
	(a)	[    ]	 	Not Applicable
	(b)	[    ]	
												
	
	3.	SEC Use Only
	
	4.	Source of Funds (See Instructions):  00
	
	5.	Check if Disclosure of Legal Proceedings Is Required 
Pursuant to Items 2(d) or 2(e):
				Not Applicable
	
	6.	Citizenship or Place of Organization:	    United States
	
	Number of	7.	Sole Voting Power:	0		
	Shares Beneficially	8.	Shared Voting Power:	2,031,626*		
	Owned by
	Each Reporting	9.	Sole Dispositive Power:	0		
	Person With	10.	Shared Dispositive Power: 
2,031,626*___
	
	11.	Aggregate Amount Beneficially Owned by Each Reporting 
Person:
          2,031,626*
	
	12.	Check if the Aggregate Amount in Row (11) Excludes Certain 
Shares
		(See Instructions):		               Not Applicable
	
	13.	Percent of Class Represented by Amount in Row (11):    
12.2%*
	
	14.	Type of Reporting Person (See Instructions):       IA, IN
	

* This is a joint filing by Austin W. Marxe (?Marxe?) and David M. 
Greenhouse (?Greenhouse?).  Marxe and Greenhouse share sole voting and 
investment power over 511,502 shares of Common Stock owned by Special 
Situations Cayman Fund, L.P., and 1,520,124 shares of Common Stock owned 
by Special Situations Fund III, L.P.  See Items 2 and 4 of this Schedule 
for additional information.*1


								Page 3 of 6 Pages
Item 1.	Security and Issuer:
	(a) XCYTE Therapies, Inc.
	(b) 1124 Columbia Street, Suite 130, Seattle, WA 98104

Item 2. (a)	Name of Person Filing:
	The persons filing this report are Austin W. Marxe (?Marxe?) 
and David M. Greenhouse (?Greenhouse?), who are the controlling 
principals of AWM Investment Company, Inc. (?AWM?), the general partner 
of and investment adviser to Special Situations Cayman Fund, L.P. 
(?Cayman?).  AWM also serves as the general partner of MGP Advisers 
Limited Partnership (?MGP?), the general partner of and investment 
adviser to Special Situations Fund III, L.P. (?SSF3?).  (SSF3 and Cayman 
will hereafter be referred to as, the ?Funds?).  The principal business 
of each Fund is to invest in equity and equity-related securities and 
other securities of any kind or nature.

             (b) Address of Principal Business Office or, if none, 
Residence:  

	The principal business address for Marxe and Greenhouse is 
153 East 53rd Street, 55th floor, New York, NY  10022.


              (c) Citizenship:

       	           Austin W. Marxe and David M. Greenhouse are 
United States citizens. 

              (d) Title of Class of Securities:  Common Stock.
	              (e) CUSIP Number:  98389F309.

Item 3.     If this statement is filed pursuant to $240.13d-1(b) or 
240.13d-2(b), check whether 
            the person filing is a:    Not Applicable

(a) ( )	Broker or Dealer registered under section 15 of the Act;
(b) ( )	Bank as defined in section 3(a) (6) of the Act;
(c) ( )	Insurance Company as defined in section 3(a) (19) of the 
Act;
(d) ( )	Investment Company registered under section 8 of the 
Investment Company Act of 1940;
(e) ( )	An Investment Adviser in accordance with $240.13d
		-1(b)(I)(ii)(E);		
(f) ( )	An employee benefit plan or endowment fund in accordance 
with $240.13d-1(b)(I)(ii)(F);


								Page 4 of 6 Pages

(g) ( )	A parent holding company or control person in accordance 
with $240.13d-
	1(b)(1)(ii)(G);
(h) ( ) 	A savings association as defined in Section 3(b) of the 
Federal Deposit Insurance 
								
	Act;
(i) ( ) 	A church plan that is excluded from the definition of an 
investment company under section 3(c)(14) of the Investment 
Company Act of 1940;
(j) ( )   	Group, in accordance with $240.13d-1(b)(1)(ii)(J).


Item 4.       Ownership:

	 (a) Amount Beneficially Owned:  Messrs. Marxe and Greenhouse 
beneficially own a total of 2,031,626 shares of Common Stock.  This 
amount includes 511,502 shares of Common Stock owned by Cayman and 
1,520,124 shares of Common Stock owned by SSF3.

	(b) Percent of Class:  Messrs. Marxe and Greenhouse beneficially 
own 12.2% of the shares outstanding.  Cayman owns 3.1% of the 
outstanding shares and SSF3 owns 9.1% of the outstanding shares. 

	(c) Number of Shares as to which the person has:
 
		(i)	Sole power to vote or to direct the vote:  0

		(ii)	Shared power to vote or to direct the vote:  2,031,626

		(iii)	Sole power to dispose or to direct the disposition of:  
0

(iv)	Shared power to dispose or to direct the disposition 
of:  2,031,626


Item 5. Ownership of Five Percent or Less of a Class:  If this statement 
is being filed to report the fact that as of the date hereof the 
reporting person has ceased to be the beneficial owner of more that five 
percent of the class of securities, check the following __.

Item 6.Ownership of More than Five Percent on Behalf of Another Person:  
Not Applicable.
						
Item 7. Identification and Classification of the Subsidiary Which 
Acquired the Security being Reported on By the Parent Holding Company:  
Not Applicable.

Item 8. Identification and Classification of Members of the Group:  Not 
applicable








         Page 5 of 6 Pages
         
Item 9. Notices of Dissolution of Group:  Not applicable.

Item 10.Certification:
	
	By signing below I certify that, to the best of my knowledge and 
belief, the securities
referred to above were acquired and are held in the ordinary course of 
business and were not 
acquired and are not held for the purpose of or with the effect of 
changing or influencing the
control of the issuer of the securities and were not acquired and are 
not held in connection with 
or as a participant in any transaction having that purpose or effect.



SIGNATURE


	After reasonable inquiry and to the best of my knowledge and 
belief, I certify that the information set forth in this statement is 
true, complete and correct.


Dated: February 3, 2005       



				/s/ Austin W. Marxe              
				AUSTIN W. MARXE
				


				/s/David M Greenhouse            
				DAVID M. GREENHOUSE





Attention:  Intentional misstatements or omissions of fact constitute 
Federal criminal violations (See 18 U.S.C. 1001).

















         								Page 6 of 6 Pages


JOINT FILING AGREEMENT


	Austin W. Marxe and David M. Greenhouse hereby agree that the 
Schedule 13G to which this agreement is attached is filed on behalf of 
each of them.



	/s/_Austin W. Marxe			
Austin W. Marxe



	/s/_David M. Greenhouse		
David M. Greenhouse




 
 
 
 
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