Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Lewis David L.
 2. Date of Event Requiring Statement (Month/Day/Year)
01/03/2014		 3. Issuer Name and Ticker or Trading Symbol
ARROWHEAD RESEARCH CORP [ARWR]
(Last)
(First)
(Middle)
ARROWHEAD RESEARCH CORPORATION, 225 S. LAKE AVENUE, SUITE 1050		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Scientific Officer
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

PASADENA, CA 91101		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option dated 10/21/2011 04/21/2012(1) 10/21/2021 Common Stock 27,500 $ 4.6 D  
Stock Option dated 02/16/2012 03/01/2012(2) 02/16/2022 Common Stock 27,000 $ 5.19 D  
Stock Option dated 09/28/2012 10/01/2012(2) 09/28/2022 Common Stock 25,000 $ 2.62 D  
Stock Option dated 05/06/2013 06/01/2013(2) 05/06/2023 Common Stock 105,000 $ 2.01 D  
Stock Option dated 09/21/2013 10/01/2013(2) 09/21/2023 Common Stock 28,000 $ 4.75 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Lewis David L.
ARROWHEAD RESEARCH CORPORATION
225 S. LAKE AVENUE, SUITE 1050
PASADENA, CA 91101		       Chief Scientific Officer  

Signatures

David L. Lewis 01/03/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Vests 1/8 on six month cliff and balance equally over 42 months
(2) Vests in 48 equal monthly installments

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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