GENERAL AMERICAN INVESTORS
                                  COMPANY, INC.





                              FIRST QUARTER REPORT
                                 MARCH 31, 2006

                         A Closed-End Investment Company
                      listed on the New York Stock Exchange





                              450 LEXINGTON AVENUE
                               NEW YORK, NY 10017
                          212-916-8400  1-800-436-8401
                       E-mail: InvestorRelations@gainv.com
                        www.generalamericaninvestors.com



                               TO THE STOCKHOLDERS
--------------------------------------------------------------------------------
For the  three  months  ended  March  31,  2006,  the  investment  return to our
stockholders   was  10.0%   (assuming   reinvestment   of  all   dividends   and
distributions).  The net asset  value per Common  Share  increased  by 4.9%.  By
comparison,  the  rate of  return  (including  income)  for our  benchmark,  the
Standard & Poor's 500 Stock Index,  was 4.2%.  For the twelve months ended March
31, 2006, the return to our  stockholders  was 29.8%,  and the return on the net
asset value per Common Share was 22.3%; these compare with a return of 11.6% for
the S&P 500.  During  each  period,  the  discount  at which our  shares  traded
fluctuated moderately and at March 31, 2006, it was 7.2%.

As set forth in the accompanying financial statements  (unaudited),  as of March
31,  2006,  the  net  assets  applicable  to the  Company's  Common  Stock  were
$1,174,679,700, equal to $40.76 per Common Share.

The increase in net assets  resulting from operations for the three months ended
March 31, 2006 was  $54,054,295.  During this period,  the net realized  gain on
securities sold was $50,519,673, and the increase in net unrealized appreciation
was $5,049,472.  Net investment income for the three months was $1,460,150,  and
distributions to Preferred Stockholders amounted to $2,975,000.

During the three  months,  228,700  shares of the  Company's  Common  Stock were
repurchased for $8,315,463 at an average discount from net asset value of 10.2%.

Equity markets continued to rally through the quarter just ended, reflecting the
continuing  resiliency of our economy in the face of rising  interest  rates and
higher commodity prices.  Our portfolio  participated in the advance,  while the
return to shareholders  benefited markedly by the decline in the discount to the
net asset value at which our shares trade.

Corporate earnings are continuing to grow, but at a moderating pace,  suggesting
that further market gains, this year, may well be tempered. We remain focused on
longer-term  trends,  confident  that  shareholders  will  be  rewarded  by  our
traditional investment practices.

We are  pleased  to  report  that on April 12,  2006,  at the  Company's  annual
meeting, the Stockholders (1) elected eleven directors,  including two directors
who were  elected  by the  holders of the  Company's  Preferred  Stock,  and (2)
ratified  the  selection of Ernst & Young LLP as auditors of the Company for the
year 2006.

Information about the Company,  including our investment  objectives,  operating
policies and procedures, investment results, record of dividend and distribution
payments,  financial reports and press releases,  is on our website and has been
updated  through  March  31,  2006.  It  can be  accessed  on  the  internet  at
www.generalamericaninvestors.com.

By Order of the Board of Directors,

General American Investors Company, Inc.

Spencer Davidson
President and Chief Executive Officer
April 12, 2006


2        STATEMENT OF ASSETS AND LIABILITIES March 31, 2006 (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors



ASSETS
------------------------------------------------------------------------------------------------------------------------------------
                                                                                        
INVESTMENTS, AT VALUE (NOTE 1a)
   Common and preferred stocks (cost $703,902,460)                                            $1,292,125,912
   Corporate note (cost $33,275,342)                                                              29,750,000
   Corporate discount notes (cost $19,963,406)                                                    19,963,406
   Money market fund (cost $28,297,721)                                                           28,297,721
                                                                                               -------------
      Total investments (cost $785,438,929)                                                    1,370,137,039

CASH, RECEIVABLES AND OTHER ASSETS
   Cash                                                                       $43,034
   Receivable for securities sold                                           9,579,291
   Dividends, interest and other receivables                                2,440,263
   Prepaid pension cost                                                     7,773,337
   Prepaid expenses and other assets                                          196,480             20,032,405
                                                                           ----------          -------------
TOTAL ASSETS                                                                                   1,390,169,444

LIABILITIES
------------------------------------------------------------------------------------------------------------------------------------
   Payable for securities purchased                                         7,776,063
   Preferred distribution accrued but not yet declared                        231,389
   Accrued pension expense                                                  5,911,460
   Accrued expenses and other liabilities                                   1,570,832
                                                                           ----------

                                                                                                  15,489,744
TOTAL LIABILITIES

5.95% CUMULATIVE PREFERRED STOCK, SERIES B -
    8,000,000 shares at a liquidation value of $25 per share (note 2)                            200,000,000
                                                                                                ------------

NET ASSETS APPLICABLE TO COMMON STOCK - 28,821,699 shares (note 2)                            $1,174,679,700
                                                                                              ==============
NET ASSET VALUE PER COMMON SHARE                                                                      $40.76
                                                                                              ==============
NET ASSETS APPLICABLE TO COMMON STOCK
------------------------------------------------------------------------------------------------------------------------------------
   Common Stock, 28,821,699 shares at par value (note 2)                  $28,821,699
   Additional paid-in capital (note 2)                                    510,885,930
   Undistributed realized gain on investments                              50,488,220
   Undistributed net investment income                                      2,992,130
   Unallocated distributions on Preferred Stock                           (3,206,389)
   Unrealized appreciation on investments                                 584,698,110
                                                                          ===========
NET ASSETS APPLICABLE TO COMMON STOCK                                                         $1,174,679,700
                                                                                              ==============
(see notes to financial statements)




3    STATEMENT OF OPERATIONS Three Months Ended March 31, 2006 (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors


INCOME
------------------------------------------------------------------------------------------------------------------------------------
                                                                                        
   Dividends (net of foreign withholding taxes of $75,509)                 $3,674,643
   Interest                                                                 1,100,652         $4,775,295
                                                                           ----------
EXPENSES
------------------------------------------------------------------------------------------------------------------------------------
   Investment research                                                      2,226,550
   Administration and operations                                              725,301
   Office space and general                                                   132,586
   Directors' fees and expenses                                                72,207
   Auditing and legal fees                                                     60,000
   Transfer agent, custodian and registrar fees and expenses                   40,783
   Stockholders' meeting and reports                                           32,107
   Miscellaneous taxes                                                         25,611          3,315,145
                                                                           ----------          ---------
NET INVESTMENT INCOME                                                                          1,460,150

REALIZED GAIN (LOSS) AND CHANGE IN UNREALIZED APPRECIATION ON INVESTMENTS (NOTES 1e AND 4)
------------------------------------------------------------------------------------------------------------------------------------



   Net realized gain on investments:
     Long transactions                                                     51,154,677
     Short sale transaction (note 1b)                                        (635,004)
                                                                           ----------
   Net realized gain on investments (long-term, except for $458,004)       50,519,673
   Net increase in unrealized appreciation                                  5,049,472
                                                                           ----------
NET GAIN ON INVESTMENTS                                                                       55,569,145

DISTRIBUTIONS TO PREFERRED STOCKHOLDERS                                                       (2,975,000)
                                                                                              ----------
INCREASE IN NET ASSETS RESULTING FROM OPERATIONS                                             $54,054,295
                                                                                             ===========

(see notes to financial statements)


4                      STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------
                           General American Investors


                                                                          Three Months
                                                                              Ended              Year Ended
                                                                         March 31, 2006         December 31,
                                                                           (Unaudited)              2005
OPERATIONS
------------------------------------------------------------------------------------------------------------------------------------
                                                                                        
   Net investment income                                                   $1,460,150            $5,408,018
   Net realized gain on investments                                        50,519,673            63,024,095
   Net increase in unrealized appreciation                                  5,049,472           103,638,830
                                                                          -----------           -----------
                                                                           57,029,295           172,070,943
                                                                          -----------           -----------
   Distributions to Preferred Stockholders:
      From net investment income                                                 -                 (845,368)
      From short-term capital gains                                              -               (2,449,640)
      From long-term capital gains                                               -               (8,604,992)
      Unallocated distributions on Preferred Stock                         (2,975,000)                -
                                                                          -----------            -----------
       Decrease in net assets from Preferred Stock distributions           (2,975,000)           (11,900,000)
                                                                          -----------            -----------

INCREASE IN NET ASSETS RESULTING FROM OPERATIONS                           54,054,295            160,170,943
                                                                          -----------            -----------
Distributions to Common Stockholders
------------------------------------------------------------------------------------------------------------------------------------
   From net investment income                                                    -               (4,333,771)
   From short-term capital gains                                                 -              (12,389,129)
   From long-term capital gains                                            (4,000,786)          (43,672,026)
                                                                          -----------           -----------
DECREASE IN NET ASSETS FROM COMMON DISTRIBUTIONS                           (4,000,786)          (60,394,926)
                                                                          -----------           -----------
Capital Share Transactions (Note 2)
------------------------------------------------------------------------------------------------------------------------------------
   Value of Common Shares issued in payment of distributions                     -                36,584,716
   Cost of Common Shares purchased                                         (8,315,463)           (39,812,172)
                                                                          -----------            -----------
DECREASE IN NET ASSETS - CAPITAL TRANSACTIONS                              (8,315,463)            (3,227,456)
                                                                          -----------            ----------
NET INCREASE IN NET ASSETS                                                 41,738,046             96,548,561
Net Assets Applicable to Common Stock
------------------------------------------------------------------------------------------------------------------------------------
BEGINNING OF PERIOD                                                     1,132,941,654          1,036,393,093
                                                                        -------------          -------------
END OF PERIOD (including undistributed net investment income of
   $2,992,130 and $1,531,980, respectively)                            $1,174,679,700         $1,132,941,654
                                                                       ==============         ==============
(see notes to financial statements)



5                             FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------
                           General American Investors

The following table shows per share operating performance data, total investment
return,  ratios and supplemental  data for the three months ended March 31, 2006
and for  each  year in the  five-year  period  ended  December  31,  2005.  This
information  has  been  derived  from  information  contained  in the  financial
statements and market price data for the Company's shares.




                                          Three Months
                                             Ended                             Year Ended December 31,
                                         March 31, 2006   ------------------------------------------------------------
                                          (Unaudited)       2005      2004      2003          2002       2001
                                         ------------     ------------------------------------------------------------
                                                                                       

PER SHARE OPERATING PERFORMANCE
   Net asset value, beginning of period      $39.00       $35.49    $33.11       $26.48       $35.14        $39.91
                                             ------       ------   -------       ------       ------        ------
      Net investment income                     .05          .19       .32          .03          .19           .41
      Net gain (loss) on investments -
        realized and unrealized                1.95         5.85      3.48         7.72        (7.88)         (.66)


      Less distributions on Preferred Stock:
        Dividends from net investment income     -          (.03)     (.09)        (.01)        (.12)         (.03)
        Distributions from net short-term
          capital gains                          -          (.08)       -            -            -           (.04)
        Distributions from net long-term
          capital gains                          -          (.30)     (.32)        (.35)        (.23)         (.29)
        Unallocated                            (.10)          -         -            -            -             -
                                             ------       ------   -------       ------       ------        ------
                                               (.10)        (.41)     (.41)        (.36)        (.35)         (.36)
                                             ------       ------   -------       ------       ------        ------
   Total from investment operations            1.90         5.63      3.39         7.39        (8.04)         (.61)
                                             ------       ------   -------       ------       ------        ------

   Less distributions on Common Stock:
        Dividends from net investment income    -           (.15)     (.23)        (.02)        (.02)         (.37)
        Distributions from net short-term
          capital gains                         -           (.44)       -            -          (.19)         (.51)
        Distributions from net long-term
          capital gains                        (.14)       (1.53)     (.78)        (.52)        (.41)        (3.28)
                                             ------       ------   -------       ------       ------        ------
                                               (.14)       (2.12)    (1.01)        (.54)        (.62)        (4.16)
                                             ------       ------   -------       ------       ------        ------

   Capital Stock transaction -
      effect of Preferred Stock offering        -             -         -          (.22)          -             -
                                             ------       ------   -------       ------       ------        ------
   Net asset value, end of period            $40.76       $39.00    $35.49       $33.11       $26.48        $35.14
                                             ======       ======   =======       ======       ======        ======

   Per share market value, end of period     $37.84       $34.54    $31.32       $29.73       $23.85        $33.47
                                             ======       ======   =======       ======       ======        ======

TOTAL INVESTMENT RETURN - Stockholder
   return, based on market price per share     9.98%*      17.40%     8.79%       27.01%      (27.21)%        4.33%
RATIOS AND SUPPLEMENTAL DATA
   Net assets applicable to Common Stock,
      end of period (000's omitted)       $1,174,680  $1,132,942 $1,036,393     $986,335     $809,192    $1,097,530
   Ratio of expenses to average net assets
      applicable to Common Stock               1.14%**     1.25%      1.15%        1.23%        0.92%         0.97%
   Ratio of net investment income to average
      net assets applicable to Common Stock    0.50%**     0.51%      0.94%        0.13%        0.61%         1.15%
   Portfolio turnover rate                     5.39%*     20.41%     16.71%       18.62%       22.67%        23.81%
PREFERRED STOCK
   Liquidation value, end of
      period (000's omitted)               $200,000    $200,000   $200,000     $200,000     $150,000      $150,000
   Asset coverage                               687%        666%       618%         593%         639%          832%
   Liquidation preference per share          $25.00      $25.00     $25.00       $25.00       $25.00        $25.00
   Market value per share                    $24.69      $24.07     $24.97       $25.04       $25.85        $25.90

   *Not annualized
   **Annualized



6             STATEMENT OF INVESTMENTS March 31, 2006 (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors


                                                                                                     Value
      Shares      COMMON AND PREFERRED STOCKS                                                      (note 1a)
------------------------------------------------------------------------------------------------------------------------------------
BUILDING AND REAL ESTATE (6.4%)
------------------------------------------------------------------------------------------------------------------------------------
                                                                                        
   1,143,041    CEMEX, S.A. de C.V. ADR                              (COST $30,440,830)           $74,617,716
                                                                                                  -----------

COMMUNICATIONS AND INFORMATION SERVICES (5.0%)
------------------------------------------------------------------------------------------------------------------------------------
     675,000    American Tower Corporation (a)                                                     20,466,000
     900,000    Cisco Systems, Inc. (a)                                                            19,503,000
     350,000    Lamar Advertising Company Class A (a)                                              18,413,500
                                                                                                   ----------
                                                                      (COST $34,761,823)           58,382,500
                                                                                                   ----------
COMPUTER SOFTWARE AND SYSTEMS (3.9%)
------------------------------------------------------------------------------------------------------------------------------------
     300,000    EMC Corporation (a)                                                                 4,089,000
   1,400,000    Microsoft Corporation                                                              38,094,000
     133,500    VeriSign, Inc. (a)                                                                  3,202,665
                                                                                                   ----------
                                                                      (COST $41,604,314)           45,385,665
                                                                                                   ----------
CONSUMER PRODUCTS AND SERVICES (2.7%)
------------------------------------------------------------------------------------------------------------------------------------
     350,000    Diageo plc                                                                         22,200,500
     175,000    PepsiCo, Inc.                                                                      10,113,250
                                                                                                   ----------
                                                                      (COST $22,493,511)           32,313,750
                                                                                                   ----------
ELECTRONICS (1.4%)
------------------------------------------------------------------------------------------------------------------------------------
     550,000    Molex Incorporated Class A                            (COST $12,287,441)           16,346,000
                                                                                                   ----------

ENVIRONMENTAL CONTROL (INCLUDING SERVICES) (4.2%)
------------------------------------------------------------------------------------------------------------------------------------
                Republic Services, Inc.                               (COST $26,227,380)           49,949,250
                                                                                                   ----------

FINANCE AND INSURANCE (27.0%)
------------------------------------------------------------------------------------------------------------------------------------
   BANKING (9.9%)
------------------------------------------------------------------------------------------------------------------------------------
     280,000    Bank of America Corporation                                                        12,751,200
     585,000    Golden West Financial Corporation                                                  39,721,500
     310,000    M&T Bank Corporation                                                               35,383,400
     475,000    North Fork Bancorporation, Inc.                                                    13,694,250
     200,000    SunTrust Banks, Inc.                                                               14,552,000
                                                                                                  -----------
                                                                      (COST $31,006,675)          116,102,350
                                                                                                  -----------
   INSURANCE (15.9%)
------------------------------------------------------------------------------------------------------------------------------------
     275,000    The Allstate Corporation                                                           14,330,250
     350,000    American International Group, Inc.                                                 23,131,500
     500,000    Annuity and Life Re (Holdings), Ltd. (a)                                              605,000
     350,000    Arch Capital Group Ltd. (a)                                                        20,209,000
         300    Berkshire Hathaway Inc. Class A (a)                                                27,105,000
     550,000    Everest Re Group, Ltd.                                                             51,353,500
     285,000    MetLife, Inc.                                                                      13,785,450
     365,000    PartnerRe Ltd.                                                                     22,662,850
     225,000    Transatlantic Holdings, Inc.                                                       13,151,250
                                                                                                  -----------
                                                                      (COST $82,551,050)          186,333,800
                                                                                                  -----------
   OTHER (1.2%)
------------------------------------------------------------------------------------------------------------------------------------
     500,000    Annaly Mortgage Management, Inc.                                                    6,070,000
   1,300,000    MFA Mortgage Investments, Inc.                                                      8,255,000
                                                                                                   ----------
                                                                      (COST $16,084,154)           14,325,000
                                                                                                  -----------
                                                                     (COST $129,641,879)          316,761,150
                                                                                                  -----------



7        STATEMENT OF INVESTMENTS March 31, 2006 (Unaudited) - continued
--------------------------------------------------------------------------------
                           General American Investors


                                                                                                     Value
      Shares      COMMON AND PREFERRED STOCKS (continued)                                          (note 1a)
------------------------------------------------------------------------------------------------------------------------------------
HEALTH CARE  (11.0%)
------------------------------------------------------------------------------------------------------------------------------------
   PHARMACEUTICALS (9.1%)
   ---------------------------------------------------------------------------------------------------------------------------------
                                                                                       
     240,000    Alkermes, Inc. (a)                                                                 $5,292,000
     170,000    Biogen Idec Inc. (a)                                                                8,007,000
     604,900    Cytokinetics, Incorporated (a)                                                      4,409,721
     305,000    Genentech, Inc. (a)                                                                25,775,550
     400,000    MedImmune, Inc. (a)                                                                14,632,000
   1,947,000    Pfizer Inc                                                                         48,519,240
                                                                                                  -----------
                                                                      (COST $67,179,843)          106,635,511
                                                                                                  -----------
   MEDICAL INSTRUMENTS AND DEVICES (1.9%)
   ---------------------------------------------------------------------------------------------------------------------------------
     450,000    Medtronic, Inc.                                       (COST $10,483,716)           22,837,500
                                                                                                   ----------

                                                                      (COST $77,663,559)          129,473,011
                                                                                                  -----------
MISCELLANEOUS (4.5%)
------------------------------------------------------------------------------------------------------------------------------------
                Other (b)                                             (COST $51,274,394)           53,090,000
                                                                                                   ----------
 OIL & NATURAL GAS (INCLUDING SERVICES) (23.4%)
------------------------------------------------------------------------------------------------------------------------------------
     665,000    Apache Corporation                                                                 43,564,150
     200,000    EOG Resources, Inc.                                                                14,400,000
     440,000    Halliburton Company                                                                32,128,800
   1,000,000    Patterson-UTI Energy, Inc.                                                         31,960,000
   1,000,000    Talisman Energy Inc.                                                               53,180,000
     330,000    Total S.A. ADR                                                                     43,470,900
   1,220,000    Weatherford International Ltd. (a)                                                 55,815,000
                                                                                                  -----------
                                                                     (COST $174,256,353)          274,518,850
                                                                                                  -----------
RETAIL TRADE (17.6%)
------------------------------------------------------------------------------------------------------------------------------------
     700,000    Costco Wholesale Corporation                                                       37,912,000
     750,000    Dollar General Corporation                                                         13,252,500
   1,570,000    The Home Depot, Inc. (c)                                                           66,411,000
   2,500,000    The TJX Companies, Inc.                                                            62,050,000
     575,000    Wal-Mart Stores, Inc.                                                              27,163,000
                                                                                                  -----------
                                                                      (COST $70,534,121)          206,788,500
                                                                                                  -----------
SEMICONDUCTORS (0.5%)
------------------------------------------------------------------------------------------------------------------------------------
     323,000    Brooks Automation, Inc. (a)                                                         4,599,520
     100,000    EMCORE Corporation (a)                                                              1,020,000
                                                                                                   ----------
                                                                       (COST $4,024,001)            5,619,520
                                                                                                   ----------
SPECIAL HOLDING (a) (d) (0.0%)
------------------------------------------------------------------------------------------------------------------------------------

     546,000    Standard MEMS, Inc. Series A Convertible Preferred     (COST $3,003,000)                    -
                                                                                                    ---------

TECHNOLOGY (2.4%)
------------------------------------------------------------------------------------------------------------------------------------
   1,900,000    Xerox Corporation (a)                                 (COST $25,689,854)           28,880,000
                                                                                                   ----------

   TOTAL COMMON AND PREFERRED STOCKS (110.0%)                        (COST $703,902,460)         1,292,125,912
                                                                                                -------------

 Principal Amount CORPORATE NOTE
------------------------------------------------------------------------------------------------------------------------------------
CONSUMER PRODUCTS AND SERVICES  (2.5%)
------------------------------------------------------------------------------------------------------------------------------------
 $35,000,000     General Motors Nova Scotia Finance Company
                   6.85% Guaranteed Notes due 10/15/08                (COST $33,275,342)           29,750,000
                                                                                                   ----------



8       STATEMENT OF INVESTMENTS March 31, 2006 (Unaudited) - continued
--------------------------------------------------------------------------------
                           General American Investors


     Principal                                                                                       Value
      Amount    SHORT-TERM SECURITY AND OTHER ASSETS                                               (note 1a)
------------------------------------------------------------------------------------------------------------------------------------
                                                                                      
 $10,000,000    General Electric Credit Corporation note due 4/11/06; 4.73% (COST $9,981,606)      $9,981,606
  10,000,000    UBS Finance Inc. Corporation note due 4/4/06; 4.68%         (COST $9,981,800)       9,981,800
  28,297,721    SSgA Prime Money Market Fund                               (COST $28,297,721)      28,297,721
                                                                                                  -----------
TOTAL SHORT-TERM SECURITIES (4.1%)                                         (COST $48,261,127)      48,261,127
                                                                                                -------------
TOTAL INVESTMENTS (e) (116.6%)                                            (COST $785,438,929)   1,370,137,039
Cash, receivables and other assets less liabilities (0.4%)                                          4,542,661
PREFERRED STOCK (-17.0%)                                                                         (200,000,000)
                                                                                               --------------
NET ASSETS APPLICABLE TO COMMON STOCK (100%)                                                   $1,174,679,700
                                                                                               ==============

 (a) Non-income producing security.
 (b) Securities which have been held for less than one year, not previously disclosed and not restricted.
 (c) 1,000,000 shares held by custodian in a segregated account as collateral for open short positions.
 (d) Restricted security acquired 12/17/99.  Fair value in the opinion of the directors.
 (e) At March 31, 2006: (1) the cost of investments for Federal income tax purposes was the same as the cost for financial reporting
     purposes, (2) aggregate gross unrealized appreciation was $602,036,783, (3) aggregate gross unrealized depreciation was
     $17,338,673, and (4) net unrealized appreciation was $584,698,110.
 
 (see notes to financial statements)


              PORTFOLIO DIVERSIFICATION March 31, 2006 (Unaudited)
--------------------------------------------------------------------------------
                            General American Investors

The  diversification  of the Company's net assets applicable to its Common Stock
by industry group as of March 31, 2006 and 2005 is shown in the following table.


                                                                              Percent Common Net Assets*
                                                  March 31, 2006                      March 31
                                            -------------------------         -------------------------
Industry Category                           Cost(000)       Value(000)           2006          2005
----------------------                      -------------------------         --------------------------
                                                                                
Finance and Insurance
   Banking                                 $31,007           $116,102            9.9%          9.7%
   Insurance                                82,551            186,334           15.9          19.2
   Other                                    16,084             14,325            1.2           1.3
                                           -------           --------           ----          ----
                                           129,642            316,761           27.0          30.2
                                           -------           --------           ----          ----
Oil and Natural Gas (Including Services)   174,256            274,519           23.4          26.5
Retail Trade                                70,534            206,788           17.6          19.6
                                           -------           --------           ----           ----
Health Care
    Pharmaceuticals                         67,180            106,636            9.1           8.7
    Medical Instruments and Devices         10,484             22,837            1.9           2.2
                                           -------           --------           ----          ----
                                            77,664            129,473           11.0          10.9
                                           -------           --------           ----          ----
Building and Real Estate                    30,441             74,618            6.4           3.9
Consumer Products and Services              55,769             62,064            5.2           3.6
Communications and Information Services     34,762             58,382            5.0           7.0
Miscellaneous**                             51,274             53,090            4.5           1.8
Environmental Control (Including Services)  26,227             49,949            4.2           3.8
Computer Software and Systems               41,604             45,386            3.9           5.1
Technology                                  25,690             28,880            2.4           0.0
Electronics                                 12,288             16,346            1.4           1.7
Semiconductors                               4,024              5,620            0.5           0.8
Special Holdings                             3,003                  -            0.0           0.0
                                           -------          ---------           ----          ----
                                           737,178          1,321,876          112.5         114.9
Short-Term Securities                       48,261             48,261            4.1           4.7
                                          --------          ---------           ----          ----
    Total Investments                     $785,439          1,370,137          116.6         119.6
                                          ========
Other Assets and Liabilities - Net                              4,543            0.4           0.0
Preferred Stock                                              (200,000)         (17.0)        (19.6)
                                                           ----------          -----         -----
Net Assets Applicable to Common Stock                      $1,174,680          100.0%        100.0%
                                                           ==========          =====         =====

*    Net Assets applicable to the Company's Common Stock.
**  Securities which have been held for less than one year, not previously disclosed and not restricted.



9                  NOTES TO FINANCIAL STATEMENTS (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors

1. Significant  Accounting  Policies - General American Investors Company,  Inc.
(the "Company"), established in 1927, is registered under the Investment Company
Act of 1940 as a closed-end,  diversified  management  investment company. It is
internally  managed  by  its  officers  under  the  direction  of the  Board  of
Directors.

The preparation of financial statements in conformity with accounting principles
generally  accepted in the United States  requires  management to make estimates
and assumptions that affect the amounts reported in the financial statements and
accompanying notes. Actual results could differ from those estimates.

a. SECURITY VALUATION  Securities traded on a national  securities  exchange are
valued at the last reported  sales price on the last business day of the period.
Securities  reported on the NASDAQ  national  market are valued at the  official
closing price on that day.  Listed and NASDAQ  securities for which no sales are
reported on that day and other securities traded in the over-the-counter  market
are valued at the last bid price (asked price for open short  positions)  on the
valuation  date.  Securities  traded  primarily in foreign markets are generally
valued at the  preceding  closing price of such  securities on their  respective
exchanges  or markets.  If,  after the close of the foreign  market,  conditions
change significantly, the price of certain foreign securities may be adjusted to
reflect fair value as of the time of the valuation of the  portfolio.  Corporate
discount notes are valued at amortized cost,  which  approximates  market value.
Investments  in money market funds are valued at their net asset value.  Special
holdings  (restricted  securities) and other securities for which quotations are
not readily available are valued at fair value determined in good faith pursuant
to procedures  established by and under the general  supervision of the Board of
Directors.

b.  SHORT  SALES The  Company  may make  short  sales of  securities  for either
speculative or hedging purposes. When the Company makes a short sale, it borrows
the securities  sold short from a broker;  in addition,  the Company places cash
with that broker and securities in a segregated account with the custodian, both
as collateral for the short  position.  The Company may be required to pay a fee
to borrow the securities and may also be obligated to pay any dividends declared
on the  borrowed  securities.  The Company  will  realize a gain if the security
price decreases and a loss if the security price  increases  between the date of
the  short  sale  and the  date on  which  the  Company  replaces  the  borrowed
securities.

c. FEDERAL INCOME TAXES The Company's  policy is to fulfill the  requirements of
the Internal  Revenue Code applicable to regulated  investment  companies and to
distribute substantially all taxable income to its stockholders. Accordingly, no
provision for Federal income taxes is required.

d. INDEMNIFICATIONS In the ordinary course of business,  the Company enters into
contracts  that contain a variety of  indemnifications.  The  Company's  maximum
exposure under these arrangements is unknown.  However,  the Company has not had
prior claims or losses pursuant to these indemnification  provisions and expects
the risk of loss thereunder to be remote.

e.  OTHER  As  customary  in  the  investment   company   industry,   securities
transactions   are  recorded  as  of  the  trade  date.   Dividend   income  and
distributions to stockholders are recorded as of the ex-dividend dates. Interest
income,  adjusted for  amortization of discount and premium on  investments,  is
earned from  settlement  date and is  recognized on the accrual  basis.  Cost of
short-term investments represents amortized cost.


2. CAPITAL STOCK AND DIVIDEND  DISTRIBUTIONS  - The authorized  capital stock of
the Company consists of 50,000,000 shares of Common Stock,  $1.00 par value, and
10,000,000  shares of  Preferred  Stock,  $1.00 par value,  of which  28,821,699
shares and 8,000,000 shares, respectively, were outstanding at March 31, 2006.

On September 24, 2003, the Company issued and sold 8,000,000 shares of its 5.95%
Cumulative Preferred Stock, Series B in an underwritten  offering. The Preferred
Shares are noncallable  for 5 years and have a liquidation  preference of $25.00
per share plus an amount equal to accumulated  and unpaid  dividends to the date
of redemption.  The underwriting discount and other expenses associated with the
Preferred  Stock  offering  amounted to  $6,700,000  and were charged to paid-in
capital.

The Company is required to allocate  distributions  from long-term capital gains
and other  types of income  proportionately  among  holders  of shares of Common
Stock and  Preferred  Stock.  To the  extent  that  dividends  on the  shares of
Preferred  Stock are not paid from long-term  capital  gains,  they will be paid
from ordinary income or net short-term  capital gains or will represent a return
of capital.

Under the Investment Company Act of 1940, the Company is required to maintain an
asset coverage of at least 200% for the Preferred  Stock. In addition,  pursuant
to the Rating Agency  Guidelines,  the Company is required to maintain a certain
discounted  asset  coverage for its  portfolio  that equals or exceeds the Basic
Maintenance  Amount  under  the  guidelines  established  by  Moody's  Investors
Service,  Inc. The Company has met these  requirements since the issuance of the
Preferred  Stock. If the Company fails to meet these  requirements in the future
and does not cure such failure,  the Company may be required to redeem, in whole
or in part,  shares of Preferred Stock at a redemption price of $25.00 per share
plus  accumulated and unpaid dividends  (whether or not earned or declared).  In
addition,   the  Company's   failure  to  meet  the  foregoing   asset  coverage
requirements  could  restrict  its ability to pay  dividends on shares of Common
Stock and could lead to sales of portfolio securities at inopportune times.

The holders of Preferred  Stock have voting  rights  equivalent  to those of the
holders of Common Stock (one vote per share) and, generally,  vote together with
the holders of Common Stock as a single class.

At all times, holders of Preferred Stock will elect two members of the Company's
Board of Directors and the holders of Preferred  and Common  Stock,  voting as a
single class,  will elect the remaining  directors.  If the Company fails to pay
dividends  on  the  Preferred  Stock  in an  amount  equal  to two  full  years'
dividends,  the  holders  of  Preferred  Stock  will  have the  right to elect a
majority of the  directors.  In  addition,  the  Investment  Company Act of 1940
requires that approval of the holders of a majority of any outstanding Preferred
Shares, voting separately as a class, would be required to (a) adopt any plan of
reorganization  that would adversely affect the Preferred Stock and (b) take any
action  requiring a vote of security  holders,  including,  among other  things,
changes in the Company's subclassification as a closed-end investment company or
changes in its fundamental investment policies.

The Company  classifies its Preferred Stock pursuant to the requirements of EITF
D-98,  Classification  and Measurement of Redeemable  Securities,  which require
that  preferred  stock for which its  redemption  is  outside  of the  company's
control should be presented outside of net assets in the statement of assets and
liabilities.



10            NOTES TO FINANCIAL STATEMENTS (Unaudited) - continued
-------------------------------------------------------------------------------
                            General American Investors

2. Capital Stock and Dividend Distributions -
                  (Continued from bottom of previous page.)

Transactions  in Common  Stock  during the three months ended March 31, 2006 and
the year ended December 31, 2005 were as follows:



                                                               SHARES                      AMOUNT
                                                       -----------------------      ---------------------
                                                         2006           2005          2006         2005
                                                       --------       --------      -------      --------
                                                                                  
Shares issued in payment of dividends
    (includes 1,067,491 shares issued from
     treasury for 2005)                                    -         1,067,491          -      $1,067,491
Increase in paid-in capital                                                             -      35,517,225
                                                                                  ----------   ----------
   Total increase                                                                       -      36,584,716
                                                                                  ----------   ----------

Shares purchased (at an average discount from net
   asset value of 10.2% and 12.4%, respectively)        228,700      1,222,404      ($228,700) (1,222,404)
Decrease in paid-in capital                                                        (8,086,763)(38,589,768)
                                                                                  -----------  ----------
   Total decrease                                                                  (8,315,463)(39,812,172)
                                                                                  -----------  ----------
Net decrease                                                                      ($8,315,463)($3,227,456)
                                                                                  ===========  ==========

At March 31, 2006, the Company held in its treasury  2,409,864  shares of Common
Stock with an aggregate cost in the amount of $69,205,977. Distributions for tax
and book purposes are substantially the same.

3.  OFFICERS'  COMPENSATION  - The  aggregate  compensation  paid by the Company
during  the three  months  ended  March 31,  2006 to its  officers  amounted  to
$1,536,125.

4.  PURCHASES AND SALES OF  SECURITIES - Purchases  and sales of securities  and
securities  sold short (other than  short-term  securities) for the three months
ended  March  31,  2006  amounted  to  $71,769,549  and   $133,765,355  on  long
transactions,  respectively,  and on short sale  transactions  $4,014,500  and
$3,379,496, respectively.

5.  PENSION  BENEFIT  PLANS - The Company has funded  (Qualified)  and  unfunded
(Supplemental)   noncontributory   defined  benefit  pension  plans  that  cover
substantially all of its employees.  The plans provide defined benefits based on
years of service and final average salary with an offset for a portion of social
security covered  compensation.  The components of the net periodic benefit cost
of the plans for the three months ended March 31, 2006 were:

                      Service cost                                $86,016
                      Interest cost                               166,039
                      Expected return on plan assets             (294,034)
                      Amortization of:
                        Prior service cost                          8,774
                        Recognized net actuarial loss (gain)       27,405
                                                                  -------
                      Net periodic benefit cost (income)          ($5,800)
                                                                  -------

The  Company  also has funded and  unfunded  contributory  defined  contribution
thrift plans that cover substantially all employees.  The aggregate cost of such
plans for the three  months  ended March 31,  2006 was  $280,358.  The  unfunded
liability  included in accrued expenses and other  liabilities at March 31, 2006
was $2,775,648.

6.  OPERATING  LEASE  COMMITMENT  - In July 1992,  the Company  entered  into an
operating  lease  agreement  for office space which expires in 2007 and provides
for  future  rental  payments  in the  aggregate  amount of  approximately  $5.6
million.  The lease  agreement  contains a clause  whereby the Company  received
twenty  months of free rent  beginning in December 1992 and  escalation  clauses
relating to operating costs and real property taxes.

Rental expense  approximated  $95,000 for the three months ended March 31, 2006.
Minimum rental commitments under the operating lease are approximately  $505,000
per annum in 2006 through 2007.

In January 2003, the Company extended a sublease agreement  (originally  entered
into in March  1996)  which  expires  in 2007 and  provides  for  future  rental
receipts.  Minimum rental receipts under the sublease are approximately $254,000
per annum in 2006 through 2007. The Company will also receive its  proportionate
share of operating expenses and real property taxes under the sublease.



11  MAJOR STOCK CHANGES*  Three Months Ended March 31, 2006 (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors



                                                                                             SHARES HELD
INCREASES                                                                  SHARES          MARCH 31, 2006
---------------------------------------------------------------------------------------------------------------
                                                                                       
NEW POSITION
   The Allstate Corporation                                                105,000             275,000 (a)

ADDITIONS
   American International Group, Inc.                                        5,000             350,000
   Everest Re Group, Ltd.                                                   10,000             550,000
   Pfizer Inc                                                              697,000           1,947,000


DECREASES
---------------------------------------------------------------------------------------------------------------
ELIMINATIONS
   Devon Energy Corporation                                                758,000                   -
   Ethan Allen Interiors Inc.                                              275,000                   -
   Telecom Corporation of New Zealand Limited                            4,600,000                   -

REDUCTIONS
   Alkermes, Inc.                                                           25,000             240,000
   Biogen Idec Inc.                                                         10,000             170,000
   EMCORE Corporation                                                       97,000             100,000
   EOG Resources, Inc.                                                     400,000             200,000
   Genentech Corporation                                                    25,000             305,000
   The Home Depot, Inc.                                                    125,000           1,570,000
   North Fork Bancorporation, Inc.                                         125,000             475,000 (a)
   PartnerRe Ltd.                                                           10,000             365,000
   Transatlantic Holdings, Inc.                                             25,000             225,000


*  Excludes transactions in Common and Preferred Stocks - Miscellaneous - Other.
(a)   Includes shares purchased in prior period and previously carried under Stocks - Miscellaneous - Other.




                            OTHER MATTERS (Unaudited)
--------------------------------------------------------------------------------
                           General American Investors

In addition to purchases of the Company's Common Stock as set forth in Note 2 on
page 10, purchases of Common Stock may be made at such times, at such prices, in
such amounts and in such manner as the Board of Directors may deem advisable.

The policies and procedures used by the Company to determine how to vote proxies
relating to portfolio  securities and the Company's  proxy voting record for the
twelve-month period ended June 30, 2005 are available:  (1) without charge, upon
request, by calling us at our toll-free telephone number  (1-800-436-8401),  (2)
on the  Company's  website  at  www.generalamericaninvestors.com  and (3) on the
Securities and Exchange Commission's website at www.sec.gov.

In addition to distributing  financial statements as of the end of each quarter,
General  American  Investors  files a Quarterly  Schedule of Portfolio  Holdings
(Form N-Q) with the  Securities and Exchange  Commission  (SEC) as of the end of
the first and third calendar quarters.  The Company's Forms N-Q are available at
www.generalamericaninvestors.com  and on the SEC's website:  www.sec.gov.  Also,
Forms N-Q may be  reviewed  and  copied at the SEC's  Public  Reference  Room in
Washington,  DC. Information on the operation of the SEC's Public Reference Room
may be obtained by calling 1-800-SEC-0330.  A copy of the Company's Form N-Q may
be obtained by calling us at 1-800-436-8401.

On May 6, 2005, the Company submitted a CEO annual certification to the New York
Stock  Exchange  ("NYSE") on which the  Company's  principal  executive  officer
certified  that he was not  aware,  as of that  date,  of any  violation  by the
Company of the NYSE's Corporate  Governance listing standards.  In addition,  as
required by Section 302 of the Sarbanes-Oxley Act of 2002 and related SEC rules,
the Company's principal executive and principal financial officer made quarterly
certifications, included in filings with the SEC on Forms N-CSR and N-Q relating
to, among other things,  the Company's  disclosure  controls and  procedures and
internal control over financial reporting, as applicable.


                                   DIRECTORS
--------------------------------------------------------------------------------
                       Lawrence B. Buttenwieser, Chairman
                  Arthur G. Altschul, Jr.     Sidney R. Knafel
                  Lewis B. Cullman            Richard R. Pivirotto
                  Spencer Davidson            D. Ellen Shuman
                  Gerald M. Edelman           Joseph T. Stewart, Jr.
                  John D. Gordan, III         Raymond S. Troubh

                      William T. Golden, Director Emeritus

                                    OFFICERS
--------------------------------------------------------------------------------

Spencer Davidson, President & Chief Executive Officer
Peter P. Donnelly, Vice-President & Trader
Sally A. Lynch, Vice-President
Eugene S. Stark, Vice-President, Administration &
     Chief Compliance Officer
Jesse R. Stuart, Vice-President
Andrew V. Vindigni, Vice-President
Diane G. Radosti, Treasurer
Carole Anne Clementi, Secretary
Craig A. Grassi, Assistant Vice-President
Maureen E. LoBello, Assistant Secretary

                                SERVICE COMPANIES
--------------------------------------------------------------------------------

Counsel
Sullivan & Cromwell LLP

Independent Auditors
Ernst & Young LLP

Custodian
State Street Bank and
  Trust Company

Transfer Agent and Registrar
American Stock Transfer & Trust
  Company
59 Maiden Lane
New York, NY  10038
1-800-413-5499
www.amstock.com





                          RESULTS OF THE ANNUAL MEETING
                                 OF STOCKHOLDERS
--------------------------------------------------------------------------------
The votes cast by stockholders at the Company's annual
meeting held on April 12, 2006 were as follows:
Election of Directors:
                              FOR       WITHHELD

Lawrence B. Buttenwieser 31,540,033     838,741
Lewis B. Cullman         31,583,948     795,127
Spencer Davidson         31,641,236     737,838
Gerald M. Edelman        31,604,421     774,653
John D. Gordan, III      31,706,826     672,248
Richard R. Pivirotto     31,595,341     783,734
D. Ellen Shuman          31,858,175     520,899
Joseph T. Stewart, Jr.   31,629,110     749,965
Raymond S. Troubh        31,624,309     754,766

Elected by holders of Preferred Stock:

Arthur G. Altschul, Jr.   6,903,727      75,655
Sidney R. Knafel          6,902,827      76,555


Ratification of the selection of Ernst & Young LLP as auditors of the Company
for the year 2006:

For - 31,843,199;        Against - 383,380;        Abstain - 152,497