---------------------------------
                                                        OMB APPROVAL
                                              ---------------------------------
                                              OMB Number:             3235-0145
                                              Expires:       February  28, 2009
                                              Estimated average burden
                                              hours per response...........10.4
                                              ---------------------------------

                                UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549


                                 SCHEDULE 13G


                   Under the Securities Exchange Act of 1934

                                (Amendment No._)*

                         CYCLACEL PHARMACEUTICALS, INC.
             -----------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
             -----------------------------------------------------
                         (Title of Class of Securities)

                                   23254L108
             -----------------------------------------------------
                                 (CUSIP Number)

                                DECEMBER 31, 2006
             -----------------------------------------------------
            (Date Of Event which Requires Filing of this Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     [x] Rule 13d-1(b)

     [ ] Rule 13d-1(c)

     [ ] Rule 13d-1(d)


*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

Persons who respond to the collection of information contained in this form are
not required to respond unless the form displays a currently valid OMB control
number.

SEC 1745 (3-06)



CUSIP No.23254L108                      13G                    Page 2 of 9 Pages
--------------------------------------------------------------------------------
   1.  NAME OF REPORTING PERSON:
       I.R.S. IDENTIFICATION NO. OF ABOVE PERSON:

       Morgan Stanley
       I.R.S. #36-3145972
--------------------------------------------------------------------------------
   2.  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP:

       (a) [ ]

       (b) [ ]
--------------------------------------------------------------------------------
   3.  SEC USE ONLY:

--------------------------------------------------------------------------------
   4.  CITIZENSHIP OR PLACE OF ORGANIZATION:

       The state of organization is Delaware.
--------------------------------------------------------------------------------
   NUMBER OF      5.   SOLE VOTING POWER:
     SHARES            1,753,144
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      6.   SHARED VOTING POWER:
      EACH             0
   REPORTING      --------------------------------------------------------------
     PERSON       7.   SOLE DISPOSITIVE POWER:
      WITH:            1,753,144
                  --------------------------------------------------------------
                  8.   SHARED DISPOSITIVE POWER:
                       0
--------------------------------------------------------------------------------
   9.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
       1,753,144
--------------------------------------------------------------------------------
  10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:

       [ ]
--------------------------------------------------------------------------------
  11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
       10.9%
--------------------------------------------------------------------------------
  12.  TYPE OF REPORTING PERSON:
       HC, CO
--------------------------------------------------------------------------------



CUSIP No.23254L108                     13G                     Page 3 of 9 Pages
--------------------------------------------------------------------------------
   1.  NAME OF REPORTING PERSON:
       I.R.S. IDENTIFICATION NO. OF ABOVE PERSON:

       FrontPoint Partners LLC
       I.R.S.  #06-1596933
--------------------------------------------------------------------------------
   2.  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP:

       (a) [ ]

       (b) [ ]
--------------------------------------------------------------------------------
   3.  SEC USE ONLY:

--------------------------------------------------------------------------------
   4.  CITIZENSHIP OR PLACE OF ORGANIZATION:

       The state of organization is Delaware.
--------------------------------------------------------------------------------
   NUMBER OF      5.   SOLE VOTING POWER:
     SHARES            1,753,144
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      6.   SHARED VOTING POWER:
      EACH             0
   REPORTING      --------------------------------------------------------------
     PERSON       7.   SOLE DISPOSITIVE POWER:
      WITH:            1,753,144
                  --------------------------------------------------------------
                  8.   SHARED DISPOSITIVE POWER:
                       0
--------------------------------------------------------------------------------
   9.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
       1,753,144
--------------------------------------------------------------------------------
  10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:

       [ ]
--------------------------------------------------------------------------------
  11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
       10.9%
--------------------------------------------------------------------------------
  12.  TYPE OF REPORTING PERSON:
       IA
--------------------------------------------------------------------------------



CUSIP No.23254L108                    13G                      Page 4 of 9 Pages

Item 1.     (a)   Name of Issuer:
                  CYCLACEL PHARMACEUTICALS INC.
                  --------------------------------------------------------------
            (b)   Address of Issuer's Principal Executive Offices:
                  150 JOHN F. KENNEDY PARKWAY
                  SUITE 100
                  SHORT HILLS, NJ 07078
                  --------------------------------------------------------------
Item 2.     (a)   Name of Person Filing:
                  (1) Morgan Stanley
                  (2) FrontPoint Partners LLC
                  --------------------------------------------------------------
            (b)   Address of Principal Business Office, or if None, Residence:
                  (1) 1585 Broadway
                      New York, NY 10036
                  (2) Two Greenwich Plaza
                      Greenwich, CT 06830
                  --------------------------------------------------------------
            (c)   Citizenship:
                  (1) The state of organization is Delaware.
                  (2) The state of organization is Delaware.
                  --------------------------------------------------------------
            (d)   Title of Class of Securities:
                  Common Stock
                  --------------------------------------------------------------
            (e)   CUSIP Number:
                  23254L108
                  --------------------------------------------------------------

Item 3.     If this statement is filed pursuant to Sections 240.13d-1(b) or
            240.13d-2(b) or (c), check whether the person filing is a:

            (a) [ ]  Broker or dealer registered under Section 15 of the Act
                     (15 U.S.C. 78o).

            (b) [ ]  Bank as defined in Section 3(a)(6) of the Act
                     (15 U.S.C. 78c).

            (c) [ ]  Insurance company as defined in Section 3(a)(19) of the Act
                     (15 U.S.C. 78c).

            (d) [ ]  Investment company registered under Section 8 of the
                     Investment Company Act of 1940 (15 U.S.C. 80a-8).

            (e) [x]  An investment adviser in accordance with Section
                     240.13d-1(b)(1)(ii)(E);
                     FrontPoint Partners LLC

            (f) [ ]  An employee benefit plan or endowment fund in accordance
                     with Section 240.13d-1(b)(1)(ii)(F);

            (g) [x]  A parent holding company or control person in accordance
                     with Section 240.13d-1(b)(1)(ii)(G);
                     Morgan Stanley

            (h) [ ]  A savings association as defined in Section 3(b) of the
                     Federal Deposit Insurance Act (12 U.S.C. 1813);

            (i) [ ]  A church plan that is excluded from the definition of an
                     investment company under Section 3(c)(14) of the
                     Investment Company Act of 1940 (15 U.S.C. 80a-3);

            (j) [ ]  Group, in accordance with Section 240.13d-1(b)(1)(ii)(J).



CUSIP No.23254L108                   13-G                      Page 5 of 9 Pages


Item 4.    Ownership as of December 31, 2006.

           (a) Amount beneficially owned:
           See the response(s) to Item 9 on the attached cover page(s).

           (b) Percent of Class:
           See the response(s) to Item 11 on the attached cover page(s).

           (c) Number of shares as to which such person has:

              (i)   Sole power to  vote or to direct  the vote:
                    See the response(s) to Item 5 on the attached cover page(s).

              (ii)  Shared power to vote or to direct the vote:
                    See the response(s) to Item 6 on the attached cover page(s).

              (iii) Sole power to dispose or to direct the disposition of:
                    See the response(s) to Item 7 on the attached cover page(s).

              (iv)  Shared power to dispose or to direct the disposition of:
                    See the response(s) to Item 8 on the attached cover page(s).

Item 5.    Ownership of Five Percent or Less of a Class.
           Not Applicable

Item 6.    Ownership of More Than Five Percent on Behalf of Another Person.

           Accounts managed on a discretionary basis by FrontPoint Partners LLC,
           a wholly owned subsidiary of Morgan Stanley, are known to have the
           right to receive or the power to direct the receipt of dividends
           from, or the proceeds from the sale of such securities.

Item 7.    Identification and Classification of the Subsidiary which Acquired
           the Security Being Reported on By the Parent Holding Company.
           See Exhibit 99.3

Item 8.    Identification and Classification of Members of the Group.
           Not Applicable

Item 9.    Notice of Dissolution of Group.
           Not Applicable

Item 10.   Certification.

           By signing below I certify that, to the best of my knowledge and
           belief, the securities referred to above were acquired and are
           held in the ordinary course of business and were not acquired and
           are not held for the purpose of or with the effect of changing or
           influencing the control of the issuer of the securities and were
           not acquired and are not held in connection with or as a participant
           in any transaction having that purpose or effect.



CUSIP No.23254L108                   13-G                      Page 6 of 9 Pages


                                  Signature.


            After reasonable inquiry and to the best of my knowledge and
            belief, I certify that the information set forth in this
            statement is true, complete and correct.


Date:       January 10, 2007

Signature:  /s/ Dennine Bullard
            --------------------------------------------------------------------

Name/Title: Dennine Bullard/Executive Director, Morgan Stanley & Co.
                            Incorporated
            --------------------------------------------------------------------
            MORGAN STANLEY


Date:       January 10, 2007

Signature:  /s/ James G. Webb
            --------------------------------------------------------------------

Name/Title: James G. Webb/Chief Financial Officer, FrontPoint Partners LLC
            --------------------------------------------------------------------
            FRONTPOINT PARTNERS LLC




EXHIBIT NO.                         EXHIBITS                                PAGE
-----------                        ----------                               ----

   99.1              Joint Filing Agreement                                   7

   99.2              Secretary's Certificate Authorizing Dennine Bullard      8
                     to Sign on behalf of Morgan Stanley

   99.3              Item 7 Information                                       9


* Attention. Intentional misstatements or omissions of fact constitute federal
  criminal violations (see 18 U.S.C. 1001).




CUSIP No.23254L108                   13-G                      Page 7 of 9 Pages


                       EXHIBIT NO. 99.1 TO SCHEDULE 13G
                            JOINT FILING AGREEMENT
              ---------------------------------------------------


                               JANUARY 10, 2007
              ---------------------------------------------------


              MORGAN STANLEY and FRONTPOINT PARTNERS LLC,

              hereby agree that, unless differentiated, this

              Schedule 13G is filed on behalf of each of the parties.


           MORGAN STANLEY

           BY: /s/ Dennine Bullard
           ---------------------------------------------------------------------
           Dennine Bullard/Executive Director, Morgan Stanley & Co. Incorporated

           FRONTPOINT PARTNERS LLC

           BY: /s/ James G. Webb
           ---------------------------------------------------------------------
           James G. Webb/Chief Financial Officer, FrontPoint Partners LLC


* Attention. Intentional misstatements or omissions of fact constitute federal
  criminal violations (see 18 U.S.C. 1001).



CUSIP No.23254L108                       13-G                  Page 8 of 9 Pages

                                   EXHIBIT NO. 99.2
                                  ------------------

                                    MORGAN STANLEY

                                SECRETARY'S CERTIFICATE


         I, Charlene R. Herzer, a duly elected and acting Assistant Secretary
         of Morgan Stanley, a corporation organized and existing under the
         laws of the State of Delaware (the "Corporation"), certify as
         follows:


             (1) Gary G. Lynch is the duly elected Executive Vice President,
                 Chief Legal Officer and Secretary of the Corporation;

             (2) Pursuant to Section 7.01 of the Bylaws of the Corporation
                 and resolutions approved by the Board of Directors of the
                 Corporation on September 25, 1998, the Chief Legal Officer
                 is authorized to enter into agreements and other instruments
                 on behalf of the Corporation and may delegate such powers
                 to others under his jurisdiction; and

             (3) Mr. Lynch signed a Delegation of Authority, dated as of
                 April 7, 2006, which authorized Stuart J. M. Breslow,
                 Dennine Bullard, John H. Faulkner, Christopher L. O'Dell
                 and Jill W. Ostergaard to sign reports to be filed under
                 Section 13 and 16 of the Securities Exchange Act of 1934
                 on behalf of the Corporation.  Such authorization is in full
                 force and effect as of this date

          IN WITNESS WHEREOF, I have hereunto set my name and affixed the seal
          of the Corporation as of the 10th day of July, 2006.

                                                ______________________________
                                                Charlene R. Herzer
                                                Assistant Secretary



CUSIP No.23254L108                    13-G                     Page 9 of 9 Pages

                                 EXHIBIT NO. 99.3
                                ------------------

                                ITEM 7 INFORMATION


             The securities being reported upon by Morgan Stanley as a parent

     holding company are owned, or may be deemed to be beneficially owned, by

     FrontPoint Partners LLC, an investment adviser in accordance with Rule

     13d-1(b)(1)(ii)(E), as amended.  FrontPoint Partners LLC is a wholly-owned

     subsidiary of Morgan Stanley.